On Tuesday 14 February 2012, three competitions were drawn in the EHF Headquarters, Vienna (AUT). The draw decided the fixtures that form the quarterfinals played in all three competitions.
CUP WINNERS CUP
Byasen VS HC Leipzig
RK Zajecar VS Dinamo Volgograd
FTC-Rail Cargo VS Zvezda Zvenigorod
Viborg HK VS DVSC-Forum Debrecen
CUP EHF
KIF Vejen VS TSV Bayer 04 Leverkusen
HBC Nimes VS Handball Club Zalau
Team Tvis Holstebro VS Lada
C.B. Mar Alicante VS Maliye Milli Piyango SK
CHALLENGE CUP
Zelina – Lokomotiva
Banik Most – H.A.C. Handball
HC Dnepryanka Kerson – Fleury Loiret Handball
Muratpasa Deletbiyesi SK – Podatkova University